I-Boc-Asp(OBut)-OH·OSu I-CAS:50715-50-9

I-Boc-Asp(OBut)-OH·OSu isetshenziswa kakhulu ekuhlanganisweni kwe-peptide ukuze kukhiqizwe ama-peptide angokwezifiso anemisebenzi ethile. Njenge-ester derivative esebenzayo, ivumela ukuhlanganiswa okulawulwayo kwe-L-aspartic acid kwamanye ama-amino acid ngesikhathi sokuhlanganiswa kwe-peptide yesigaba esiqinile (i-SPPS). Le nqubo ebalulekile ibalulekile ekutholakaleni nasekuthuthukisweni kwemithi, kanye nasezifundweni ze-biochemical ezihlose ukuqonda ukusebenzisana kwamaprotheni kanye nezindlela zokubonisa izimpawu. Ngaphezu kwalokho, i-Boc-Asp(OBut)-OH·OSu idlala indima ebalulekile ekudalweni kwemitapo yolwazi ye-peptide yokuhlola imithi kanye nokwenza ngcono i-lead. Ubumsulwa bayo obuphezulu kanye nekhwalithi ehambisanayo kuqinisekisa ukuthembeka kanye nokuphindaphindeka ezinqubweni zocwaningo, okunikela ekuthuthukisweni emikhakheni esukela kumakhemikhali wezokwelapha kuya kubuchwepheshe be-bio. Ngamafuphi, i-Boc-Asp(OBut)-OH·OSu ibalulekile ekuthuthukisweni kokutholwa kwesayensi nezokwelapha ngokuvumela ukuhlanganiswa kwama-peptide ayinkimbinkimbi anezakhiwo ezilungiselelwe, ekugcineni isekela ukuthuthukiswa kwemithi emisha kanye nezidakamizwa zokwelapha. Ukusetshenziswa kwayo kabanzi ocwaningweni lwemithi kugcizelela ukubaluleka kwayo njengethuluzi eliwusizo kososayensi nabacwaningi emhlabeni jikelele.