I-Boc-Asn-ONp CAS:4587-33-1

I-Boc-Asn-ONp isetshenziswa kakhulu ekuhlanganisweni kwe-peptide ekukhiqizweni kwama-peptide enziwe ngokwezifiso anemisebenzi ethile. Isebenza njenge-ejenti yokuhlanganisa, ikhuthaza ukunamathiswa kwe-L-asparagine kwamanye ama-amino acid ngesikhathi sokwakheka kwe-peptide bond. Lokhu kubalulekile ekudaleni ukulandelana kwe-peptide ngemisebenzi yebhayoloji elungiselelwe wena, okufaka isandla ekutholakaleni nasekuthuthukisweni kwemithi, kanye nezifundo ze-biochemical ezihlose ukuqonda ukusebenzisana kwamaprotheni kanye nezindlela zokubonisa izimpawu. Ngaphezu kwalokho, i-Boc-Asn-ONp idlala indima ebalulekile ekuhlanganisweni kwe-peptide yesigaba esiqinile (i-SPPS) njenge-ester esebenzayo, okuvumela ukuhlanganiswa okusebenzayo nokulawulwa kwama-peptide ekusekelweni okuqinile. Ubumsulwa bayo obuphezulu kanye nekhwalithi ehambisanayo kuqinisekisa ukuthembeka nokuphindaphinda ezinqubweni zocwaningo, okwenza kube ithuluzi eliwusizo kososayensi nabacwaningi abasebenza emikhakheni eyahlukahlukene, kusukela ocwaningweni oluyisisekelo kuya ekuthuthukisweni kwemithi emisha kanye nama-compounds e-bioactive. Ngamafuphi, i-Boc-Asn-ONp ibalulekile ekuthuthukisweni kokutholwa kwesayensi nezokwelapha ngokuvumela ukuhlanganiswa kwama-peptide ayinkimbinkimbi anezakhiwo ezilungiselelwe wena, ekugcineni isekele ukuthuthukiswa kwemithi emisha kanye nama-ejenti okwelapha. Ukusetshenziswa kwayo kabanzi ocwaningweni lwezokwelapha kugcizelela ukubaluleka kwayo njengethuluzi eliwusizo kososayensi nabacwaningi emhlabeni jikelele.