I-Amphotericin B CAS:1397-89-3 Intengo Yomkhiqizi

I-Amphotericin B inemisebenzi eminingi yokulwa nesikhunta, okwenza isebenze kahle ngokumelene nesikhunta esihlukahlukene, okuhlanganisa imvubelo kanye nesikhunta. Ivame ukusetshenziselwa ukwelapha izifo ezinkulu zesikhunta ezingamelani neminye imithi yokulwa nesikhunta.

I-Amphotericin B isebenza ngokubopha ku-ergosterol ekhona kulwelwesi lweseli lesikhunta, okubangela ukwakheka kwama-pores. Lokhu kuholela ekuphumeni kwezingxenye ezibalulekile kusuka kuseli futhi ekugcineni ukufa kwesikhunta.

I-Amphotericin B ivame ukusetshenziselwa ukutheleleka kwesikhunta okungenayo, njenge-candidemia (ukutheleleka kwe-Candida okujwayelekile), i-cryptococcal meningitis, kanye ne-invasive aspergillosis. Ingasetshenziswa futhi ekwelapheni ukutheleleka kwesikhunta ezigulini ezinezivikeli mzimba ezisengozini, njengalezo ezine-HIV/AIDS noma ezifakelwa izitho zomzimba.