(i-alpha, i-gamma)-i-gamma-[(3-Carboxy-1-oxopropyl)amino]-i-alpha-methyl-[1,1'-biphenyl]-4-pentanoicacid4-ethylestercalciumusawoti(2:1) I-CAS:1369773-39-6

I-compound (alpha,gammas)-gamma-[(3-Carboxy-1-oxopropyl)amino]-alpha-methyl-[1,1'-biphenyl]-4-pentanoicacid4-ethylestercalciumsalt(2:1) ihlolwe ngokusetshenziswa kwayo okungaba khona emikhakheni yezokwelapha neyezokwelapha. Ibonisa ithemba ekwelapheni izimo ezihlobene nokuntuleka kwe-calcium noma ukuphazamiseka kwe-metabolic lapho kudingeka khona i-calcium supplementation. Le compound ingase ibe nokusetshenziswa empilweni yamathambo, njengoba i-calcium ibalulekile emandleni nasekuqineni kwamathambo. Ingahlolwa ngendima yayo ekuphathweni kwe-osteoporosis, ekwelapheni ukuphuka, noma njengesengezo sokudla ukusekela impilo yamathambo iyonke. Ngaphezu kwalokho, ucwaningo luphakamisa ukuthi le compound ingaba nomthelela empilweni yenhliziyo nemithambo yegazi, ukusebenza kwemisipha, kanye nokudluliselwa kwemizwa ngenxa yezindima ezibalulekile ze-calcium kulezi zinqubo zomzimba. Amandla ayo njengomthombo we-calcium onezici ezithile ze-bioavailability kwenza kube yinto efanelekile yokutadisha okwengeziwe ekuthuthukiseni izindlela zokwelapha ezihlose izifo ezihlobene ne-calcium. Ngamafuphi, ukusetshenziswa okunezinhlangothi eziningi kwe-(alpha,gammas)-gamma-[(3-Carboxy-1-oxopropyl)amino]-alpha-methyl-[1,1'-biphenyl]-4-pentanoicacid4-ethylestercalciumsalt(2:1) kugcizelela ukubaluleka kwayo ekubhekaneni nezinkinga zezempilo ezihlobene ne-calcium kanye nokuthuthukisa ukungenelela kokwelapha kwezokwelapha kanye nokunakekelwa kwempilo.