(2S,4R)-4-aMinopyrrolidine-2-carboxylic acid hydrochloride CAS:16257-89-9

I-(2S,4R)-4-aminopyrrolidine-2-carboxylic acid hydrochloride idlala indima ebalulekile ocwaningweni nasekuthuthukisweni kwemithi, isebenza njengesisekelo esibalulekile sokulungiselela ama-peptide ayinkimbinkimbi nama-peptidomimetics anemisebenzi ehlukahlukene ye-bio kanye namandla okwelapha. Ukufakwa kwayo kumaketanga e-peptide kusiza ekudalweni kwamakhemikhali ahlobene nemithi, kufaka phakathi ama-peptide hormone, ama-enzyme inhibitors, kanye nezidakamizwa, ngaleyo ndlela kunegalelo ekwakhiweni kwezindlela zokwelapha ezintsha zezimo ezahlukene zezokwelapha. Ngaphezu kwalokho, le nhlanganisela isetshenziswa ekuhlanganisweni kwe-peptide yesigaba esiqinile (i-SPPS), okuvumela ukuhlanganiswa okusebenzayo nokulawulwayo kochungechunge lwe-peptide oluyinkimbinkimbi. Ukuhambisana kwayo nezindlela ze-SPPS kuvumela ukukhiqizwa kwama-peptide angokwezifiso kanye nemitapo ye-peptide esetshenziswa ezifundweni zezinto eziphilayo, ukuhlolwa kwezidakamizwa, kanye nocwaningo lwe-biochemical, okubonisa indima yayo ebalulekile ekuthuthukisweni kobuchwepheshe obusekelwe kuma-peptide. Ngaphezu kwalokho, i-(2S,4R)-4-aminopyrrolidine-2-carboxylic acid hydrochloride isetshenziswa emalabhorethri ezemfundo nawezimboni ukuphenya ukusabela kwe-peptide, ubudlelwano besakhiwo nomsebenzi, kanye namasu okuguqulwa kwe-peptide, okusekela intuthuko kumakhemikhali e-peptide kanye nokutholakala kwezidakamizwa. Ukusetshenziswa okunezinhlangothi eziningi kwe-(2S,4R)-4-aminopyrrolidine-2-carboxylic acid hydrochloride kugcizelela indima yayo ebalulekile ocwaningweni lwe-peptide, ukwenziwa kwemithi, kanye nokuthuthukiswa kwezindlela zokwelapha ezisekelwe ku-peptide, okuqhuba intuthuko kwezobuchwepheshe be-bio kanye nekhemistri yezokwelapha.