(2S,4R)-4-amino-1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid I-CAS:132622-69-6

I-(2S,4R)-4-amino-1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid isebenza njengesisekelo esibalulekile ekwakhiweni kwama-peptide nama-peptidomimetics anemisebenzi ehlukahlukene ye-bio kanye namandla okwelapha. Ukufakwa kwayo kumaketanga e-peptide kusiza ekudalweni kwamakhemikhali ahlobene nemithi, kufaka phakathi ama-peptide hormone, ama-enzyme inhibitors, kanye nezidakamizwa ezingaba khona. Ngaphezu kwalokho, le nhlanganisela isetshenziswa ekulungiseleleni imithi esekelwe kuma-peptide ngezinjongo zocwaningo, zokuxilonga, kanye nokwelapha, inegalelo ekuthuthukisweni kokwelashwa okusha kwezimo ezahlukene zezokwelapha. Ngaphezu kwalokho, i-(2S,4R)-4-amino-1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid isetshenziswa kakhulu ekwakhiweni kwe-solid-phase peptide (SPPS), okuvumela ukuhlanganiswa okusebenzayo nokulawulwayo kwe-complex peptide sequences. Ukuhambisana kwayo nezindlela ze-SPPS kuvumela ukukhiqizwa kwama-peptide enziwe ngokwezifiso kanye nemitapo yolwazi yama-peptide esetshenziswa ezifundweni zezinto eziphilayo, ukuhlolwa kwezidakamizwa, kanye nocwaningo lwe-biochemical, okugqamisa indima yayo ebalulekile ekuthuthukisweni kobuchwepheshe obusekelwe kuma-peptide. Ngaphezu kwalokho, le nhlanganisela isetshenziswa emalabhorethri ezemfundo kanye nezimboni ukuphenya ngokusabela kwe-peptide, ubudlelwano besakhiwo nomsebenzi, kanye namasu okuguqula i-peptide, okusekela intuthuko kumakhemikhali e-peptide kanye nokutholakala kwemithi. Sekukonke, ukusetshenziswa okunezinhlangothi eziningi kwe-(2S,4R)-4-amino-1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid kugcizelela indima yayo ebalulekile ocwaningweni lwe-peptide, ukwenziwa kwemithi, kanye nokuthuthukiswa kwezokwelapha okusekelwe ku-peptide, okuqhuba intuthuko kubuchwepheshe be-bio kanye nekhemistri yezokwelapha.