2,3,5,6-Di-O-isopropylidene-α-D-mannofuranose CAS:14131-84-1

Umphumela we-2,3,5,6-Di-O-isopropylidene-α-D-mannofuranose ukunikeza isivikelo kumaqembu e-hydroxyl ku-molecule ye-mannose. Le nhlanganisela yakha isivikelo esizungezile amaqembu e-hydroxyl ezindaweni 2, 3, 5, kanye no-6, ivimbela ukusabela okungafuneki ukuthi kwenzeke kulezo zindawo. Ukusetshenziswa okuyinhloko kwe-2,3,5,6-Di-O-isopropylidene-α-D-mannofuranose kusemkhakheni we-carbohydrate chemistry kanye nokwakheka kwayo. Ama-carbohydrate angama-molecule abalulekile ahilelekile ezinqubweni ezahlukahlukene zebhayoloji njengokuqashelwa kwamaseli, ukubonakaliswa kwamaseli, kanye nokusabela komzimba. Ngokuvikela ngokukhetha amaqembu athile e-hydroxyl ku-molecule ye-mannose, osokhemisi bangalawula futhi bashintshe amanye amaqembu asebenzayo ngaphandle kokuthinta ama-hydroxyls avikelwe. Le nhlanganisela ithola usizo ekuhlanganisweni kwama-carbohydrate ayinkimbinkimbi nama-glycoconjugates. Ama-Glycoconjugates ama-molecule aqukethe ingxenye ye-carbohydrate enamathele kwenye i-molecule, njengeprotheni noma i-lipid. Lawa ma-molecule adlala indima ebalulekile ezinhlelweni zezinto eziphilayo, okuhlanganisa ukunamathela kwamaseli, impendulo yomzimba, kanye nokuqashelwa kwezifo. Ngokusebenzisa i-2,3,5,6-Di-O-isopropylidene-α-D-mannofuranose, abacwaningi bangethula izinguquko ezindaweni ezithile ze-molecule ye-mannose ngaphakathi kwe-glycoconjugate, ngaphandle kokuphazamisa amaqembu e-hydroxyl avikelwe. Lokhu kwenza kube nokwenzeka ukwenziwa kwama-glycoconjugates enziwe ngokwezifiso ukuze kusetshenziswe izinhlelo ezahlukene, njengokuthuthukiswa kwemithi, ukuxilongwa, kanye nokwakhiwa kwemithi yokugoma. Ngamafuphi, umphumela we-2,3,5,6-Di-O-isopropylidene-α-D-mannofuranose ukuvikela amaqembu e-hydroxyl ku-molecule ye-mannose, futhi ukusetshenziswa kwayo kusekuhlanganisweni kwama-carbohydrate ayinkimbinkimbi nama-glycoconjugates ngokusetshenziswa okungenzeka emikhakheni eyahlukene yocwaningo kanye nemboni.