I-2-chloroadenosine CAS:146-77-0

2-I-Chloroadenosine isebenza izindima eziningana ezibalulekile emikhakheni ehlukene. Ocwaningweni lwezemithi, icwaningwa ngamandla ayo njenge-antiviral kanye ne-anticancer agent ngenxa yomthelela wayo ku-metabolism ye-nucleic acid. Njenge-purine analog, i-2-Chloroadenosine ikhombisa izakhiwo ezithembisayo zokwelapha umdlavuza oqondiwe futhi ihlolwa ngekhono layo lokuvimbela ukwanda kwamaseli futhi ibangele i-apoptosis kumaseli omdlavuza. Ngaphezu kwalokho, isebenza njengesikhungo esibalulekile ekuhlanganisweni kwezinto eziphilayo zokulungiselela amakhemikhali asebenzayo ngokwemithi kanye ne-nucleoside derivatives. Isakhiwo sayo esiyingqayizivele siphinde siyibeke njengengxenye ebalulekile ekuthuthukisweni kwama-nucleic acid aguquliwe ngezinjongo zocwaningo kanye nokwelapha. Ngaphezu kwalokho, i-2-Chloroadenosine isetshenziswa njengethuluzi locwaningo ezifundweni ezihlobene ne-nucleic acid chemistry, i-epigenetics, kanye ne-molecular biology, okufaka isandla ekuqondeni kwethu ukusebenzisana kwe-DNA ne-RNA kanye nokuguqulwa. Ukuguquguquka kwayo kanye nomthelela wayo ongaba khona kwezemithi, ucwaningo lwama-molecular, kanye nezicelo zezokwelapha kugqamisa ukubaluleka kwayo njenge-chemical compound ebalulekile.