2′-(4-METHYLUMBELLIFERYL)-ALPHA-DN-ACETYLNEURAMINIC ACID SODIUM SALT CAS:76204-02-9

I-2′-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid usawoti we-sodium iyinhlanganisela yamakhemikhali evame ukusetshenziswa ekuhloleni nasekuhloleni ucwaningo.Iwukuphuma okune-fluorescent okubhalwe ukuthi i-sialic acid, uhlobo lwe-carbohydrate etholakala ebusweni bamaseli.

Le nhlanganisela isetshenziswa njenge-substrate yama-enzyme abizwa ngokuthi ama-neuraminidases, asebenza ukususa izinsalela ze-asilic acid kuma-glycoprotein nama-glycolipids.Uma lawa ma-enzyme enza ku-2′-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid usawoti we-sodium, ukhulula umkhiqizo we-fluorescent owaziwa ngokuthi i-4-methylumbelliferon.

I-fluorescence ekhiqizwa yi-compound ingalinganiswa futhi inqunywe, inikeze ulwazi ngomsebenzi we-neuraminidase enzymes.Lokhu kuwusizo ikakhulukazi ekutadisheni izifo ezihlukahlukene nezimo ezihlobene ne-aberrant sialic acid metabolism.

Inhlanganisela iphinde isetshenziselwe izinjongo zokuxilonga, njengokutholwa kwezifo ezibangelwa amagciwane ezibandakanya umsebenzi we-neuraminidase.Kulezi zivivinyo, inhlanganisela isetshenziselwa ukukhomba ukuba khona kwezinhlobo ezithile zegciwane noma ukuhlola ukusebenza kwe-neuraminidase inhibitors ekwelashweni kwe-antiviral.

Oda noma Cela I-Quote

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Isicelo kanye Nomphumela

I-Neuraminidase Activity Assay: Le nhlanganisela ijwayele ukusetshenziselwa ukukala umsebenzi wama-enzayimu e-neuraminidase kumasampula ebhayoloji.Ngokuqapha i-fluorescence ekhiqizwayo, abacwaningi bangakwazi ukunquma izinga lomsebenzi we-neuraminidase, ongasiza ekutadisheni izifo nezimo ezihlukahlukene.

Ukutholwa Kokutheleleka Ngegciwane: Izifo eziningi zegciwane, kuhlanganise nomkhuhlane, zibandakanya umsebenzi we-neuraminidase.Le nhlanganisela ingasetshenziswa ukuthola kanye nokulinganisa ubukhona bezinhlobo ezithile zegciwane ngokulinganisa umsebenzi we-fluorescent.Kuwusizo ikakhulukazi ekuhloleni ukusebenza kwe-neuraminidase inhibitors ekwelashweni ngezidambisigciwane.

Ukuhlaziywa kweGlycosylation: I-Sialic acid iyisakhi esibalulekile sama-glycoprotein nama-glycolipids.Ngokuhlanganisa i-2'-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid usawoti we-sodium ekuhlolweni, abacwaningi bangathola ukuqonda ku-sialic acid metabolism, amaphethini e-glycosylation, nezinqubo ezihlobene nokusebenza komzimba.

Ukutholwa Kwezidakamizwa: I-Neuraminidase inhibitors iyikilasi lezidakamizwa ezisetshenziswa ekwelapheni izifo ezibangelwa amagciwane.Le nhlanganisela ingasetshenziswa ezifundweni zokutholwa kwezidakamizwa, isiza abacwaningi ukuthi babone futhi bahlole ama-inhibitor angaba khona omsebenzi we-neuraminidase.

Ukupakishwa komkhiqizo:

Ulwazi Olwengeziwe:

Ukwakheka	I-C21H26NNAO11
Isivivinyo	99%
Ukubukeka	Impushana emhlophe
Inombolo ye-CAS.	76204-02-9
Ukupakisha	Ezincane nezinkulu
I-Shelf Life	iminyaka engu-2
Isitoreji	Gcina endaweni epholile neyomile
Isitifiketi	ISO.