1-(3-Dimethylaminopropyl)-3-ethylcarbodiimidehydrochloride CAS:25952-53-8

Ezindaweni zocwaningo kanye nezindawo zelebhu, i-1-(3-Dimethylaminopropyl)-3-ethylcarbodiimidehydrochloride isetshenziswa kabanzi ekuhlanganiseni amaprotheni, ama-peptide, nama-nucleic acid kwamanye ama-molecule kanye nezindawo. Indima yayo ekuhlanganiseni ama-biomolecule isekela ukuthuthukiswa kokuxilonga, ukwelashwa, kanye nezinto eziphilayo, okuvumela ukudalwa kwama-bioconjugates amasha anemisebenzi ethile kanye nezakhiwo zokubopha. Ngaphezu kwalokho, le nhlanganisela isebenza njenge-reagent ebalulekile ekwakhiweni kwe-peptide, lapho isetshenziselwa khona ukusebenzisa amaqembu e-carboxyl kuma-amino acid, okwenza kube lula ukuhlangana kwawo namaqembu e-amine ukwakha izibopho ze-peptide. Ukusetshenziswa kwayo kumakhemikhali e-peptide kusekela ukulungiswa kwama-peptide angokwezifiso, imitapo yolwazi ye-peptide, kanye nama-peptide conjugates ezifundweni zezinto eziphilayo, ukutholakala kwemithi, kanye nezicelo zokwelapha. Ngaphezu kwalokho, i-1-(3-Dimethylaminopropyl)-3-ethylcarbodiimidehydrochloride ithola ukusetshenziswa ekuthuthukisweni komjovo kanye nobunjiniyela bamaprotheni, okufaka isandla ekuguqulweni nasekusebenzeni kwama-molecule e-immunogenic. Ngokuvumela ukuhlanganiswa kwama-antigen kanye nama-adjuvant, kusekela ukukhiqizwa kwemithi yokugomela kanye nama-immune-modulating agents ocwaningo lokuvimbela izifo kanye ne-immunotherapy. Ngaphezu kwalokho, le nhlanganisela isetshenziswa ekuvimbeleni ukuhamba kwama-biomolecule ezisekelweni nasezindaweni eziqinile, idlala indima ebalulekile ekuthuthukisweni kwama-biosensors, ukuhlolwa kokuxilonga, kanye namadivayisi e-bioanalytical. Amandla ayo okwenza kube lula ukuxhumana okuzinzile kwe-covalent kusekela ukwakhiwa kwamapulatifomu asebenzayo okuthola nokufunda ukusebenzisana kwezinto eziphilayo kanye nezinqubo. Sekukonke, i-1-(3-Dimethylaminopropyl)-3-ethylcarbodiimidehydrochloride idlala indima ebalulekile ekuhlanganiseni kwezinto eziphilayo, ukwakheka kwama-peptide, ukuthuthukiswa kwemijovo, kanye nokusetshenziswa kwezinto eziphilayo, okubonisa ukubaluleka kwayo ocwaningweni lwezokwelapha, isayensi yezokwelapha, kanye ne-biotechnology.