I-α-Galactosidase CAS:9025-35-8

i-α-galactosidase(α-galactosidase, α-gal, EC 3.2.1.22) iyi-exoglycosidase ekhuthaza i-hydrolysis yezibopho ze-α-galactosidic. Ngenxa yokuthi ingabolisa i-melibiose, ibizwa nangokuthi i-melibiase, ekhuthaza i-hydrolysis yezibopho ze-α-galactosidic. Lesi sici siyenza ibe usizo ekuthuthukiseni nasekuqedeni izingxenye ezilwa nokudla okunempilo ekudleni okusekelwe ekudleni nasekudleni okusekelwe ku-soya. Ngaphezu kwalokho, ingafeza ukuguqulwa kohlobo lwegazi lwe-B→O emkhakheni wezokwelapha, ilungiselele igazi lomhlaba wonke, futhi idlale indima ebalulekile ekwelashweni kokushintsha kwe-enzyme yesifo se-Fabry. I-α-galactosidase ingasebenza futhi kuma-polysaccharides ayinkimbinkimbi, ama-glycoprotein kanye nama-glycosphingoses aqukethe izibopho ze-α-galactosidic. Amanye ama-α-galactosidases angaphinde aguqule i-galactosylate lapho ukuhlushwa kwe-substrate kucebiswe kakhulu, futhi lesi sici singasetshenziswa ekuhlanganiseni ama-oligosaccharides kanye nokulungiselela ama-derivatives e-cyclodextrin. Ukuthuthukiswa kwe-neutrophil noma i-α-galactosidase eqinile ne-pH kanye nokusesha ama-microorganism noma izitshalo ezikhiqiza ama-enzyme amaningi kuye kwaba izindawo ezidumile zocwaningo eminyakeni yamuva nje. Ama-α-galactosidases amaningi amelana nokushisa nawo avuse kancane kancane isithakazelo esikhulu kososayensi ngenxa yobuchwepheshe bawo, elindele ukusebenzisa ukuzinza kwawo kokushisa ukudlala inani elikhulu lokusetshenziswa embonini, nokukhombisa ububanzi bezicelo emkhakheni wezobuchwepheshe, ubuchwepheshe kanye nemithi.